Special

MmuEX6005995 @ mm10

Exon Skipping

Gene
ENSMUSG00000030102 | Itpr1
Description
inositol 1,4,5-trisphosphate receptor 1 [Source:MGI Symbol;Acc:MGI:96623]
Coordinates
chr6:108482897-108542064:+
Coord C1 exon
chr6:108482897-108483007
Coord A exon
chr6:108485243-108485338
Coord C2 exon
chr6:108541903-108542064
Length
96 bp
Sequences
Splice sites
3' ss Seq
CCTTGGTTCTCTCCGTTTAGAAC
3' ss Score
8.37
5' ss Seq
CTGGTGAGT
5' ss Score
10.1
Exon sequences
Seq C1 exon
AACTGCATCGCCACCCACGAGTCCAATGGCATCGATATCATCACAGCCCTCATCCTCAATGATATCAACCCTCTGGGAAAGAAGCGGATGGACCTGGTGTTAGAACTGAAG
Seq A exon
AACAATGCTTCGAAGCTGCTACTGGCCATCATGGAAAGCAGACACGATAGTGAAAATGCAGAGAGGATCCTGTACAACATGAGGCCCAAGGAGCTG
Seq C2 exon
GAAAGAAACCTTGATTGGTTCCCCAGAATGAGAGCCATGTCCCTGGTCAGCAGCGATTCTGAAGGGGAACAGAACGAGCTGAGGAACCTGCAGGAGAAGCTGGAGTCTACCATGAAGCTGGTCACCAATCTTTCTGGCCAGCTGTCAGAACTAAAGGACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000030102_MULTIEX1-48/59=47-C2
Average complexity
C3
Mappability confidence:
97%=98=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.062 C2=0.359
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF084546=RIH_assoc=PD(18.3=59.5)

							
A:
NO

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000032192





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000144880
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm9




Conservation


Human
(hg38)
chr3:4779550-4779645 
HIGH PSI
HsaEX1018100
(ITPR1)
Human
(hg19)
chr3:4821234-4821329 
Rat
(rn6)
chr4:140516562-140516657 
HIGH PSI
RnoEX0045402
(Itpr1)
Cow
(bosTau6)
chr22:21682394-21682489 
Chicken
(galGal4)
chr12:18502983-18503078 
HIGH PSI
GgaEX6010805
(ITPR1)
Chicken
(galGal3)
chr12:19147292-19147387 
HIGH PSI
GgaEX6010805
(Q9DEX2_CHICK)
Zebrafish
(danRer10)
chr11:35575524-35575619 
HIGH PSI
DreEX6092767
(itpr1b)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GAAAGAAGCGGATGGACCTGG

				
R: 
AGCTGGCCAGAAAGATTGGTG

				
Band lengths: 
178-274

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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