DmeEX0003204 @ dm6
Exon Skipping
Gene
FBgn0036043 | CG8177
Description
The gene Anion exchanger 2 is referred to in FlyBase by the symbol DmelAe2 (CG8177, FBgn0036043). It is a protein_coding_gene from Dmel. It has 14 annotated transcripts and 14 polypeptides (8 unique). Gene sequence location is 3L:9763544..9786466. Its molecular function is described by: inorganic anion exchanger activity. It is involved in the biological process described with: intracellular pH reduction; regulation of intracellular pH; bicarbonate transport. 22 alleles are reported. The phenotypes of these alleles manifest in: digestive system; material anatomical entity; basal stalk; follicle stem cell; gut section. The phenotypic classes of alleles include: viable; lethal; size defective; decreased fecundity; increased cell number; increased cell death. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 18-24 hour embryonic stages.
Coordinates
chr3L:9763986-9779593:+
Coord C1 exon
chr3L:9763986-9764193
Coord A exon
chr3L:9771655-9771919
Coord C2 exon
chr3L:9779446-9779593
Length
265 bp
Sequences
Splice sites
3' ss Seq
TTTGTTTTTTCTACTTTCAGGGC
3' ss Score
11.36
5' ss Seq
AAGGTGAGT
5' ss Score
10.47
Exon sequences
Seq C1 exon
CGCCGCGTAAACTAAAACTAAATTTAAAAAACTAAGAAAAAAACATATACGAGGAAGTTGACTCCGCAAGATCAAGGTTAAAGAAAAACCCTTTATGCTAATCAACAAGCTGTGTGTGAGGCACAGTGGAAAATTTTCGAATTTCGCCAAGCGGCGACGTCATCAGTGGTCGCATTTGTTGTTGTTGGCGCCCGTGGCCGAGTAAAAG
Seq A exon
GGCGTTGAATTCGCTGCCCCGAATGCCGAGATTCTTGCAGCATCCACAGTGGCCGCAGCAAATAACCAAGCCCACCAGCACCCCGATGCCATTGCATTGCCTGATCATCAAATAAGCGCATTCAATAATTCCCATATCTTAGGATTGGATCTAAATTAAACGAAATCTTTCTAAAACAACACTCAAGATGAGCTTCAGTTCGGCCAGCGGCAGGGAGAATAATGTCCGCAAATTATCCTTCCTGGGCTTCAATACCAAAAAGAAG
Seq C2 exon
TCTGGCAATGAGGATCCCGACGAGGTGCTGCTGGACTCGGAAATGGACAAGGTCTTTGCCGGCAACAGTGCGCGCAAGGACAAGTTCGATGTAAACACCTTCCAGGACAACTCCCAGCTGCCCATTGGATCCCGCAAGAAGAATAGCA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0036043-'4-8,'4-4,9-8
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref, Alt. ATG (>10 exons))
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.579 C2=0.872
Domain overlap (PFAM):
C1:
NA
A:
NO
C2:
NO
Main Inclusion Isoform:
FBpp0076047
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0076046, FBpp0076048, FBpp0076049, FBpp0076050, FBpp0076053, FBpp0076054, FBpp0076055, FBpp0076056, FBpp0304232
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TACGAGGAAGTTGACTCCGCA
R:
CTTCTTGCGGGATCCAATGGG
Band lengths:
302-567
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)