DmeEX0004077 @ dm6
Exon Skipping
Gene
FBgn0011763 | Dp
Description
The gene DP transcription factor is referred to in FlyBase by the symbol DmelDp (CG4654, FBgn0011763). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2R:13222433..13228202. Its molecular function is described by: transcription factor binding; DNA-binding transcription factor activity, RNA polymerase II-specific; protein binding; DNA binding; sequence-specific DNA binding. It is involved in the biological process described with 10 unique terms, many of which group under: response to stress; eggshell chorion gene amplification; dorsal/ventral axis specification, ovarian follicular epithelium; regulation of cell development; regulation of transcription, DNA-templated. 43 alleles are reported. The phenotypes of these alleles manifest in: egg; imaginal tissue; cuticle; dopaminergic neuron; external encapsulating structure. The phenotypic classes of alleles include: decreased cell death; cell death defective; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, in adult female stages.
Coordinates
chr2R:13226404-13226929:+
Coord C1 exon
chr2R:13226404-13226639
Coord A exon
chr2R:13226700-13226782
Coord C2 exon
chr2R:13226846-13226929
Length
83 bp
Sequences
Splice sites
3' ss Seq
TTTCCCATATATCGTTTCAGGTC
3' ss Score
10.54
5' ss Seq
TGGGTGAGT
5' ss Score
8.73
Exon sequences
Seq C1 exon
ACATTTCTGGCCCTGGAAGAGGAAAACTGTCAGCGCCGCGAGCGAATAAAACAGAAAAACGAAATGTTGCGCGAAATGATCATGCAGCATGTGGCGTTCAAGGGATTGGTCGAGCGGAACAAGCGAAACGAGAGCCAAGGCGTGGTGCCTTCCCCGAATGCCTCGATCCAGCTACCGTTCATCATCGTGAACACGCACAAGTCCACGAAAATCAACTGCAGTGTGACCAACGACAA
Seq A exon
GTCCGAATACATATTCAAGTTCGACAAAACCTTCGAAATGCACGATGACATTGAGGTGCTCAAGCGTATGGGATTCCTATTGG
Seq C2 exon
GACTGGATAAGGGCGAATGCACGCCGGAGAACATTGAACGAGTCAAGTCGTGGGTGCCTCCAAACCTTGCCAAATACGTAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0011763-'12-12,'12-11,13-12
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.139 A=0.000 C2=0.103
Domain overlap (PFAM):
C1:
PF0208610=MethyltransfD12=FE(60.0=100),PF087815=DP=FE(54.2=100)
A:
PF0208610=MethyltransfD12=PD(15.4=69.0),PF087815=DP=FE(19.4=100)
C2:
PF087815=DP=FE(19.4=100)
Main Inclusion Isoform:
FBpp0086853

Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0086854, FBpp0305354
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
AACAAGCGAAACGAGAGCCAA
R:
CACCCACGACTTGACTCGTTC
Band lengths:
175-258
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)