DmeEX0005317 @ dm6
Exon Skipping
Gene
FBgn0259111 | Ndae1
Description
The gene Na[+]-driven anion exchanger 1 is referred to in FlyBase by the symbol DmelNdae1 (CG42253, FBgn0259111). It is a protein_coding_gene from Dmel. It has 11 annotated transcripts and 11 polypeptides (10 unique). Gene sequence location is 2L:7223328..7249343. Its molecular function is described by: inorganic anion exchanger activity; anion:anion antiporter activity; sodium:bicarbonate symporter activity. It is involved in the biological process described with 6 unique terms, many of which group under: transport; establishment of localization; ion transmembrane transport; localization; inorganic ion transmembrane transport. 16 alleles are reported. The phenotype of these alleles manifest in: imaginal disc. The phenotypic classes of alleles include: viable; lethal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 18-24 hour embryonic stages.
Coordinates
chr2L:7223328-7227346:-
Coord C1 exon
chr2L:7227104-7227346
Coord A exon
chr2L:7225606-7225856
Coord C2 exon
chr2L:7223328-7223697
Length
251 bp
Sequences
Splice sites
3' ss Seq
ATGCCAATTTTATATTGAAGGAC
3' ss Score
5.48
5' ss Seq
CCAGTAAGT
5' ss Score
9.09
Exon sequences
Seq C1 exon
GTTCCCATTAAACGCGTCCACCTGTTCACCATGATCCAGCTGGCCTGCCTCATAATTCTCTGGCTGATCAAGTCCTTCTCACAGACATCCATTCTGTTTCCCCTGATGTTGGTGGTGATGATTGGCATCAGAAAGGCCCTGGATCTGGTGTTCACTCGGCGCGAGCTGAAGATCCTGGACGACATAATGCCGGAGATGACGAAGCGTGCGGCGGCGGATGATCTGCATAAACTGGACGCTGAG
Seq A exon
GACAATCATCATCAGCACCCCCCAGGATCTGGGGCGGGGGCCAACTACAATGCCGATAAGTCGGGTCCCACGACCATTCACATTCCGCTCTCCGGGAACAAAACCGGCACCAAGGGACCCACAGTGAACATTCCCCAGGAGGCTGTCAATCGCACCGCAGTCTGGCAGCAGATCAACAAGGATGGCAACGGCATCTCGGAGCAACTGATCATACCAGTCACCCTTAAAGTCCGCCAGATCAATGGCAACCA
Seq C2 exon
AACCCAAAATTTAATACGTCGAAGCAATTGTGGCGTGGATATCTTACACCAACAGAAACATCCGTTTGAGTCAATGATTTAATTCATTTTATCGTATATCTGTGTACCTGTAAATCAATTACGTGTCTATAATCAGTCCTAATACTTATGATGTATATGTACCATCACCTACCGTCCCTTTTGCGTATATATATATATATATATATATATATATATATATGCTTATATATACCCCATTTGTGCGATTTGGCACAAACTAATTGTCTGGCAACATATCATGCGACTACTCGGAAACCAATCGTATACAATCCACAGTAAAGGAATTTGTTGAAATAAATGTATAAAATAAAGTTACATATTTTGGACTCAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0259111_MULTIEX1-9/9=8-C2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
In the CDS, with uncertain impact
No structure available
Features
Disorder rate (Iupred):
C1=0.029 A=0.720 C2=0.408
Domain overlap (PFAM):
C1:
PF0095516=HCO3_cotransp=PD(2.2=13.6)
A:
NO
C2:
NO
Main Inclusion Isoform:
FBpp0304048
Main Skipping Isoform:
FBpp0304054
Other Inclusion Isoforms:
FBpp0288814
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATTGGCATCAGAAAGGCCCTG
R:
AAAGGGACGGTAGGTGATGGT
Band lengths:
304-555
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)