Special

DmeEX0009777 @ dm6

Exon Skipping

Gene
Description
The gene swiss cheese is referred to in FlyBase by the symbol Dmelsws (CG2212, FBgn0003656). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is X:7956820..7968236. Its molecular function is described by: lysophospholipase activity; protein binding; protein kinase A catalytic subunit binding. It is involved in the biological process described with 11 unique terms, many of which group under: multicellular organismal process; programmed cell death; cellular lipid metabolic process; apoptotic process; cellular process. 32 alleles are reported. The phenotypes of these alleles manifest in: cellular anatomical entity; cytoplasm; organelle; adult sense organ; cell body rind of lamina. The phenotypic classes of alleles include: short lived; phenotype; phototaxis defective; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during late pupal stages, in stages of adults of both sexes.
Coordinates
chrX:7957866-7960112:-
Coord C1 exon
chrX:7959996-7960112
Coord A exon
chrX:7958271-7958482
Coord C2 exon
chrX:7957866-7958210
Length
212 bp
Sequences
Splice sites
3' ss Seq
TTTCCTTGGCCACCATTTAGCCG
3' ss Score
2.61
5' ss Seq
GAGGTACAT
5' ss Score
6.75
Exon sequences
Seq C1 exon
GATCTCTGTGGCGTTACGTACGCTCCTCCATGTCGCTCAGTGGCTACATGCCGCCGTTATGCGATCCTAAAGATGGGCACCTCTTGCTGGATGGCGGCTATGTGAATAATCTGCCAG
Seq A exon
CCGATGTGATGCATAATCTTGGAGCTGCTCACATAATCGCCATCGATGTGGGATCCCAGGATGACACTGACCTGACCAACTATGGCGACGACCTAAGCGGTTGGTGGCTGCTCTACAAGAAATGGAATCCCTTCACATCGCCTGTGAAGGTGCCCGACTTGCCGGACATCCAATCCCGACTAGCCTATGTGTCCTGCGTACGCCAACTAGAG
Seq C2 exon
GAGGTCAAAAACTCCGACTACTGCGAGTATATCCGACCGCCGATCGATAAGTACAAGACTCTAGCCTTCGGCAGCTTCGACGAAATTCGAGACGTGGGCTATGTGTTTGGCAAAAACTACTTTGAGAGCATGGCCAAGGCTGGTCGATTGGGCCGCTTCAATCAGTGGTTCAACAAAGAGCCACCCAAGCGGGTTAACCATGCCTCCCTCAACGAGTACACGTTCATCGATCTGGCGCAGATCGTGTGCCGTCTGCCGGAGACATACGCCGTGAATACCGCGGAACTCTTTAGCGAGGACGAAGACTGTGATGGCTACATTTCGGAGCCGACCACACTGAATACG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0003656-'11-10,'11-9,16-10
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.070
Domain overlap (PFAM):

C1:
PF0173417=Patatin=FE(23.4=100)
A:
PF0173417=Patatin=PD(2.4=5.6)
C2:
NO


Main Inclusion Isoform:
FBpp0071077


Main Skipping Isoform:
NA


Other Inclusion Isoforms:
FBpp0071078, FBpp0290889


Other Skipping Isoforms:
NA
Associated events
Primers PCR
Suggestions for RT-PCR validation
F:
CGTTACGTACGCTCCTCCATG
R:
GGGTGGCTCTTTGTTGAACCA
Band lengths:
292-504
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)