DmeEX6023852 @ dm6
Exon Skipping
Gene
FBgn0039581 | Moca-cyp
Description
The gene Moca-cyp is referred to in FlyBase by the symbol DmelMoca-cyp (CG1866, FBgn0039581). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3R:28340334..28345169. Its molecular function is described by: cyclosporin A binding; peptidyl-prolyl cis-trans isomerase activity. It is involved in the biological process described with: protein peptidyl-prolyl isomerization; protein folding; mRNA splicing, via spliceosome. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages.
Coordinates
chr3R:28340334-28342214:+
Coord C1 exon
chr3R:28340334-28340738
Coord A exon
chr3R:28341372-28341459
Coord C2 exon
chr3R:28341627-28342214
Length
88 bp
Sequences
Splice sites
3' ss Seq
AATCCGATTCCTCTTTCCAGATG
3' ss Score
9.03
5' ss Seq
TATGTAAGT
5' ss Score
6.69
Exon sequences
Seq C1 exon
CCCTAGTTCTGAGTAGAGCTGGCAACGCCGACATTGTGCAACTCGAAAACGGCGTGAAATACGTATTAAACAGCATTTATTGGCAGAAATCGGCGCATATAATGACGGTAAACAAACGCGACGCGGGTGCCACGCGACCGCGGTGCTTCTTTGACATTTCCCTGGGCGGCCTGGGCATGGGCCGCATTGTCTTCGAGCTCTTCAACGATGTGGCGCCCAAAACGGCCGAAAATTTCCGCGCACTCTGCACGGGCGAAAAGGGATTTGGCCTAATCACCGGCAAGAAGCTGCAGTACAAGGGTGTGATATTCCACCGGGTGGTCAAGGACTTCATGGTCCAGGCGGGCGACTTCTCTGCGGGCAACGGCACCGGCGGCGAGTCCATCTACGGCGGGACGTTCGAGG
Seq A exon
ATGAGAGCTTCGAAAAGAAGCACGATCGTCCCTTCCTGCTGTCGATGGCCAACCGGGGCAAGAACACAAATGGCTCGCAGTTCTTTAT
Seq C2 exon
CCTTAGCCCGTGGGCGTTAAAGTGTGAGCTAGCGTCCCACTGACCAGCGGACAGATGCATCGCAATCTGTCCTCCATCGGCCGATGCACCGCCATCCCAGCATCCCTAGTGCATTTGGTCTGTGGGTCCAAAAACCAAGCGAAAGACGATGCAGGTCTTTCAGCTCCATGGTCTTTGGTCCCTGGGCCTGGGTCTCAGTGTGTGTCTCAATCTCTCTCTCTCTCGCTGTCGGCTCCTTGTGGATCTTTGCGGGAATCTTGGGCTGGATCCTCACGATGGATCTGCCAGATGACAATGTGCTGGCCATGGCCAGCGGCAGCGGCTCTTGCGGTTGGTGGCTTGCCAAAATCCTGTGTGCCACCTCTGCCTACACACCTAGAAACCTTTAAACTTTGTTGCACATGACATTGTCTCCGCCACAACCGACAACAATAACAACAACAACAACTGAAACAACAACAACAACACCGATTTCAACTACAACTGCCTACTGCAGCCCA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0039581-'0-4,'0-0,2-4=AN
Average complexity
A_C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.020 A=0.333 C2=0.273
Domain overlap (PFAM):
C1:
PF0016016=Pro_isomerase=PU(51.8=84.3)
A:
PF0016016=Pro_isomerase=FE(17.5=100)
C2:
PF0016016=Pro_isomerase=FE(6.0=100)
Main Inclusion Isoform:
FBpp0084655
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
GGGATTTGGCCTAATCACCGG
R:
AGCTCACACTTTAACGCCCAC
Band lengths:
176-264
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)