Special

MmuEX0036987 @ mm9

Exon Skipping

Gene
ENSMUSG00000029913 | Prdm5
Description
PR domain containing 5 [Source:MGI Symbol;Acc:MGI:1918029]
Coordinates
chr6:65781243-65831136:+
Coord C1 exon
chr6:65781243-65781365
Coord A exon
chr6:65819175-65819259
Coord C2 exon
chr6:65831043-65831136
Length
85 bp
Sequences
Splice sites
3' ss Seq
CAGTTTAATCTTTTTTTCAGATT
3' ss Score
8.05
5' ss Seq
CAGGTGAAT
5' ss Score
6.6
Exon sequences
Seq C1 exon
GTACGTGGGAGCAAGGGAGAAGTTCTGTATATTTTGGATGCTACCAACCCAAGACACTCCAACTGGCTTCGCTTTGTTCACGAGGCACCATCTCAGGAGCGGAAGAACCTGGCTGCCATTCAA
Seq A exon
ATTCATGAGATATTTGATTGTCAAGAATGTATGAAAAAGTTTATTTCTGCTAATCAGCTGAAGCGTCACATGATTACCCACTCAG
Seq C2 exon
ACCCACTCCGAGGAGAGACCTTTCCAGTGTGATGCATGTAAAGCCTTGTTCCGCACGCCCTTTTCTCTGCAGAGACACCTGTTAATCCACAACA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000029913_MULTIEX1-5/11=C1-7
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.191 A=0.023 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF156161=TerY-C=PU(20.3=36.6),PF042167=FdhE=PU(30.4=51.2),PF134651=zf-H2C2_2=PU(4.8=2.4),PF102764=zf-CHCC=PU(5.0=2.4),PF132481=zf-ribbon_3=PU(0.1=0.0)

							
A:
PF128742=zf-met=PD(4.3=3.4),PF144711=DUF4428=FE(56.0=100),PF134651=zf-H2C2_2=PU(38.5=34.5)

							
C2:
PF121713=zf-C2H2_jaz=PD(8.0=6.2),PF134651=zf-H2C2_2=PU(38.5=31.2)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000031976





     
                   









    
Main Skipping Isoform:
ENSMUSP00000031976f2652A





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000031973, ENSMUSP00000031976f2653A, ENSMUSP00000031976f2654A, ENSMUSP00000133423
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
chr4:120799661-120799745 
HIGH PSI
HsaEX6086002
(PRDM5)
Human
(hg19)
chr4:121720816-121720900 
HIGH PSI
HsaEX6086002
(PRDM5)
Rat
(rn6)
chr4:96744220-96744304 
HIGH PSI
RnoEX0069366
(Prdm5)
Cow
(bosTau6)
chr6:4622428-4622512 
HIGH PSI
BtaEX0028371
(PRDM5)
Chicken
(galGal4)
chr4:53686928-53687012 
HIGH PSI
GgaEX6035035
(PRDM5)
Chicken
(galGal3)
chr4:55813232-55813316 
HIGH PSI
GgaEX6035035
(PRDM5)
Zebrafish
(danRer10)
chr23:1995510-1995594 
HIGH PSI
DreEX0058026
(prdm5)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TGGGAGCAAGGGAGAAGTTCT

				
R: 
GCGGAACAAGGCTTTACATGC

				
Band lengths: 
172-257

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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