DmeEX6002393 @ dm6
Exon Skipping
Gene
FBgn0000535 | eag
Description
The gene ether a go-go is referred to in FlyBase by the symbol Dmeleag (CG10952, FBgn0000535). It is a protein_coding_gene from Dmel. It has 8 annotated transcripts and 8 polypeptides (7 unique). Gene sequence location is X:14955477..15009989. Its molecular function is described by: voltage-gated cation channel activity; voltage-gated potassium channel activity; ion channel binding. It is involved in the biological process described with 11 unique terms, many of which group under: cognition; behavior; multicellular organismal process; learning or memory; transport. 31 alleles are reported. The phenotypes of these alleles manifest in: cytoplasm; organelle; nervous system; myofibril; cellular anatomical entity. The phenotypic classes of alleles include: mating defective; phenotype; sensory perception defective; behavior defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed during late larval stages, during early pupal stages.
Coordinates
chrX:14990320-14993558:+
Coord C1 exon
chrX:14990320-14990432
Coord A exon
chrX:14992720-14992851
Coord C2 exon
chrX:14993446-14993558
Length
132 bp
Sequences
Splice sites
3' ss Seq
TCCGATTCGCATACCCGCAGAAA
3' ss Score
7.29
5' ss Seq
GAGGTAAGT
5' ss Score
11.08
Exon sequences
Seq C1 exon
ATGCGGCTTCATGTATGGCGAGCTGACAGACAAGGAGACGGTGGGACGGCTGGAGTACACGCTGGAGAACCAACAGCAGGATCAGTTCGAGATTTTGCTGTACAAGAAGAACA
Seq A exon
AAACCCCACTATGGCTGCTGCTACAGGTCGCACCCATACGCAACGAACGCGACCTGGTGGTGCTCTTCCTGCTGACCTTCCGGGACATCACGGCCCTCAAGCAGCCCATCGACAGCGAGGACACGAAGGGAG
Seq C2 exon
TTTTAGGTCTCTCGAAATTCGCCAAATTGGCAAGATCAGTGACACGGAGTCGCCAGTTCAGCGCCCATCTGCCCACGCTAAAGGATCCCACGAAGCAGTCCAATTTGGCGCAT
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0000535-'7-8,'7-6,9-8=AN
Average complexity
A_C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF134261=PAS_9=FE(29.7=100)
A:
PF134261=PAS_9=PD(24.2=68.9)
C2:
NO
Main Inclusion Isoform:
FBpp0301719

Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0073772, FBpp0110308, FBpp0292377, FBpp0292378, FBpp0301717, FBpp0301718
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
ATGCGGCTTCATGTATGGC
R:
ATGCGCCAAATTGGACTGCTT
Band lengths:
226-358
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)