DmeEX6009353 @ dm6
Exon Skipping
Gene
FBgn0027561 | CG18659
Description
This gene is referred to in FlyBase by the symbol DmelCG18659 (FBgn0027561). It is a protein_coding_gene from Dmel. It has 8 annotated transcripts and 8 polypeptides (6 unique). Gene sequence location is 2R:9123304..9132030. Its molecular function is described by: Rab GTPase binding; phosphatidylinositol phosphate binding; Rab guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: regulation of Rab protein signal transduction; endocytic recycling; endocytosis. 8 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period.
Coordinates
chr2R:9124744-9126213:-
Coord C1 exon
chr2R:9126181-9126213
Coord A exon
chr2R:9125551-9126066
Coord C2 exon
chr2R:9124744-9125220
Length
516 bp
Sequences
Splice sites
3' ss Seq
CCGCTATTTAATCTTCTCAGGTT
3' ss Score
7.55
5' ss Seq
AGCGTAAGT
5' ss Score
10.07
Exon sequences
Seq C1 exon
ACTAATCCGGCTGTAAAGTCTGCCGTCAAATCG
Seq A exon
GTTAAGGAGGGCTCGCGGGGCATGAAGACCGCCTATAAGGGATTCAAGACAAAGCTGCGCGAGAACGGAAACCAGTTTGGTGGCACGCACTTCCACTTTGGACTTGGCTCCCCGAATCATTCGGATCGTCCTGACGGCACCAGCGGAGGATACGTTCGTGGTGGCAAGGCCATCGGGGCTGCACACCACTCGGCGCCCAGTTCTCCAGTGACCAGCAAGCGTCTTGATGGAATTGCCTCCGTCACGGGAAGCAGCGGCAGCGGTGGATCCGGCGCCAGGGAGCCGCGGGAGTTCCTGCGACGCGGTCCCGTCCCGCTGGCCATGTCTAGCTCGAGCAGCCACATTCAGCCGAACGGCCATGCGTACGGTGCGAGTGCTGGTGCTCATTATGGTCATCATCTCGCTGCGTCTCCTGCTGTTAGCTCGGCGAGCTCGCTCTGCTCATCTTCGGAGATGAACCTGTCGCAGGAACTGCAGAACCATCCGCTTTTCAAGACGCCGGCAGTGGACCGCAGC
Seq C2 exon
CTTAAGCCAAACGCAGAGCACAGGCGAGGAGCAGCACCGCCAGCCCGTCCACCGCCACCGCAATCTACGCCCGCCTCCTACTACAATCATCCCTATGCCGCGCATCCGCACGTGGAGTCTAAGCCGCCAAGGCACACCTCCACGCCCACCAGACCGCGTCAGCCCCTGCCTACCGCCGATTCCAGCAGCTTTGATAGTCCGCCGGACGTACAATCTCCACCGATTCCGCCCCGGAGGCAGGGCAGCTCGAATGCGATTGTGGCGGCCACGGCTGCAGCCGTCAGTGCAGAGATTAGCAAACTGGAACGTAACTGCTGGAAGGACGAGCCCGGAAATGATTCTGTACGCAGCTCGAATGCATCCTCGTCATCGGCGACCTCATCCTCCTCGGGCGCATCGTTTGTGACGGCGGCGTCGACGTTCTCGCATCTTAATGTGTCTGATCCGCCCATTCCGACACCGCGGGCCAAGAGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0027561-'14-12,'14-11,15-12=AN
Average complexity
A_C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.727 A=0.847 C2=0.898
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
FBpp0087707
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0291659, FBpp0291660, FBpp0297474, FBpp0308463
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
GGCTGTAAAGTCTGCCGTCAA
R:
GCTCGTCCTTCCAGCAGTTAC
Band lengths:
353-869
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)