DmeEX6021993 @ dm6
Exon Skipping
Gene
FBgn0013812 | Dhc93AB
Description
The gene Dynein heavy chain at 93AB is referred to in FlyBase by the symbol DmelDhc93AB (CG3723, FBgn0013812). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:21024580..21042499. Its molecular function is described by: ATP-dependent microtubule motor activity, minus-end-directed; dynein intermediate chain binding; ATP binding; dynein light intermediate chain binding. It is involved in the biological process described with: microtubule-based movement; sensory perception of sound; cilium movement. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: auditory perception defective; neurophysiology defective; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of no expression detected. Peak expression observed in adult male stages.
Coordinates
chr3R:21031400-21032160:-
Coord C1 exon
chr3R:21031799-21032160
Coord A exon
chr3R:21031582-21031738
Coord C2 exon
chr3R:21031400-21031519
Length
157 bp
Sequences
Splice sites
3' ss Seq
AATAATGACGCTACTTTCAGGAT
3' ss Score
5.46
5' ss Seq
AAGGTTTCT
5' ss Score
0.28
Exon sequences
Seq C1 exon
GGATTGCTGTTCAGTTCGACAGAGTGCTTGACGGGCTCCACAGATCTTATACGCTTGTGGCAGCACGAGACACAGAGGGTGTACTCGGATAAGCTAACGGACGATAAGGACATCGATAGCTTTACCAAGATGCAGCATGACATTGTCAAGAAGTCATTCGAGGAAATTGACGAGTCCGTCATATTCGACAAGCCGAATATTTACTGTCATTTCGCTGGAGGAATTGGTGATCCTAAGTACATGCCCATCAAGGGTTGGCCTGAGCTTCACAAACTCCTTCAGGAAGCAATGTCATCGTATAATGATCTAGTCGCTGCCATGAACCTGGTGCTATTCGAGGATGCGATGATGCACGTATGCAG
Seq A exon
GATCAATCGCATTTTAGAATCACCGCGTGGCAGCGCCTTATTGGTTGGTGTTGGTGGCAGCGGGAAACAATCTCTAGCGCGCTTGGCAGCATTCATATCCAGCTTGGAGGTCGTGCAGATACAGCTGAAAAAGGGTTACGGAGTCAATGACTTGAAG
Seq C2 exon
AATGAATTTTCAGGACTTTATTTAAAGGCCGGACTAAAGAACGTTGGCATTATGTTCCTAATGACGGATGCGCAGATCCCCAGCGAGGACTTCCTCGTCTTGATCAACGATATGCTAGCG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0013812-'15-16,'15-15,16-16=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF127752=AAA_7=PD(8.1=18.2),PF127802=AAA_8=PU(7.8=17.4)
A:
PF127802=AAA_8=FE(19.4=100)
C2:
PF127802=AAA_8=FE(14.6=100)
Main Inclusion Isoform:
FBpp0307750
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0271744
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
TCGAGGAAATTGACGAGTCCG
R:
TGCCAACGTTCTTTAGTCCGG
Band lengths:
254-411
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)