DmeEX6015520 @ dm6
Exon Skipping
Gene
FBgn0035879 | GAPcenA
Description
The gene GTPase activating protein and centrosome-associated is referred to in FlyBase by the symbol DmelGAPcenA (CG7112, FBgn0035879). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:8346561..8352279. Its molecular function is described by: GTPase activator activity; Rab GTPase binding. It is involved in the biological process described with: regulation of GTPase activity; intracellular protein transport; activation of GTPase activity; positive regulation of GTPase activity. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 and 12-24 hour embryonic stages, during late larval stages, during early pupal stages.
Coordinates
chr3L:8348749-8350867:+
Coord C1 exon
chr3L:8348749-8349845
Coord A exon
chr3L:8349900-8350088
Coord C2 exon
chr3L:8350148-8350867
Length
189 bp
Sequences
Splice sites
3' ss Seq
AATTGGAAATTTACTTGTAGGAA
3' ss Score
4.73
5' ss Seq
CATGTAAGT
5' ss Score
8.31
Exon sequences
Seq C1 exon
AGTCGGCCAGCGAAATGCGTATTATGGACCATTTTATGTCAAAGCGACCCATGACGTTACGATTCTATTTGCATCTAAAGCGGACCGAAGAGTCCAACTGGAAAGTGAATAGCATTGATCCCTCTGAGGAAATAACGGAGCAGCCGGGCCACCAGCAAAGCTCTTCCCTGCTCAAGATGGGTATGAATAATCTATCGCGCATTGTGCGCAGTTCGTCCATTGCCTCGATTGAGGATGATTGTCCCTCGGACTACAGCAGCGATGGGGATGAGCCGCTGCTGAGTGGCACTGGTGAGGTATCTAAGGATTGCTCGCAGGACACGCTCGACGAATGGGATCCCATTCTGCGTGAGTGGGATTCCGAGAAGAGACCGAAAAATCTGGCACCTTTAGTACGCCTCGGCGTTCCAGAAGCACTGCGTGAAAAGATCTGGCAGAAGCTAGCCAACGTCGAGGGCAGAATGGAAATGAACGACAAGTACAAGATCTTAATCACCAAA
Seq A exon
GAAACCAAATGTGAGACCGTTATCCAGCGGGACATCCATCGCACTTTCCCGGCGCACAAATGCTTCAAAGAAATTGGCGGTTCTGGCCAAGATGCACTTTTTAAGGTGTCCAAAGCGTATGCCGTTCATGACAGCGAGGTTGGATATTGTCAGGGTCTAAGTTTCATAGCAGCTAGTCTGCTCCTTCAT
Seq C2 exon
ATGCCTGAGGAGGATGCGTTCTGTGTTCTGGTAGCGCTTATGTACGACTATGGGCTCCGTGATCTCTACAAAGCCGGATTCGAGGTCCTTTACCTTCGTCTCTACCAACTGGAGCGACTGATCAAGGATCAGCTGCCCAAGCTGCACGAACACTTCACGGCCTGCGGCATTGAGACGCACATGTACGCCTCCCAATGGTTCCTAACCTTATATACAGCGCGATTCCCATTGTGTTTTGTGTTCCACGTGCTGGATGTGTTTCTACTGGACGGACTACCTGTGCTCTTCCAGGTGGCCGTTACTCTCTTATCAATCTGTGAATCCGACTTGCGGCAACTCGATTTTGAGGGCATTCTAAAGTATTTCCGGGTAACGTTGCCGAAAAAGTGCCGCAGCTCCAGTCAGGCACGCAAGGTGATGAAGCAAGCCTGCGAACGTAAGATAAAAAAACTGAAGCAGTACGAGGAGGAGTTCCTGCTGAAGAAGCAGCACAAGGAGCG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0035879-'4-7,'4-6,5-7=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.169 A=0.000 C2=0.163
Domain overlap (PFAM):
C1:
PF0064018=PID=PD(8.2=2.7),PF124733=DUF3694=WD(100=40.4),PF0056613=RabGAP-TBC=PU(14.2=7.9)
A:
PF0056613=RabGAP-TBC=FE(30.4=100)
C2:
PF0056613=RabGAP-TBC=PD(53.9=45.8)
Main Inclusion Isoform:
FBpp0112066
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0076332
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
GGATCCCATTCTGCGTGAGTG
R:
TAAAGGACCTCGAATCCGGCT
Band lengths:
258-447
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)