DmeEX6022955 @ dm6

Exon Skipping

Gene

FBgn0000036 | nAChRalpha1

Description

The gene nicotinic Acetylcholine Receptor alpha1 is referred to in FlyBase by the symbol Dmel AChRalpha1 (CG5610, FBgn0000036). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3R:24393896..24457157. Its molecular function is described by: neurotransmitter receptor activity; acetylcholine-gated cation-selective channel activity; acetylcholine receptor activity. It is involved in the biological process described with 8 unique terms, many of which group under: cellular process; cell communication; signaling; biological regulation; synaptic signaling. 26 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; chemical resistant; some die during pupal stage; memory defective; fertile; lethal - all die before end of pupal stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed within 12-24 hour embryonic stages, during early larval stages.

Coordinates

chr3R:24404682-24407498:-

Coord C1 exon

chr3R:24407318-24407498

Coord A exon

chr3R:24404969-24405429

Coord C2 exon

chr3R:24404682-24404893

Length

461 bp

Sequences

Splice sites

3' ss Seq

ATTTATCGAATCTTTTCCAGGTG

3' ss Score

9.2

5' ss Seq

TAGGTAAGA

5' ss Score

9.14

Exon sequences

Seq C1 exon

CGCCGATGGCAACTATGAAGTGACAATAATGACAAAAGCAATTCTTCATCACACGGGCAAAGTGGTGTGGAAACCGCCCGCCATTTACAAATCCTTCTGCGAAATTGATGTCGAGTACTTTCCCTTCGACGAGCAGACATGTTTCATGAAGTTCGGATCCTGGACCTACGATGGTTACATG

Seq A exon

GTGGACTTGAGGCACTTGAAGCAGACCGCCGACTCGGACAACATCGAGGTGGGCATCGACCTGCAGGACTACTACATCTCCGTGGAGTGGGACATCATGCGTGTGCCGGCGGTGCGGAACGAGAAGTTCTACAGCTGCTGCGAGGAGCCGTATCTGGACATAGTGTTCAACCTGACGCTCCGCCGGAAGACGCTCTTCTACACGGTCAACCTGATCATACCCTGCGTGGGCATCTCGTTCCTGTCCGTTCTGGTCTTCTACCTGCCCAGCGACTCTGGCGAGAAGATCTCGCTCTGCATCAGCATCCTGCTCTCGCTTACCGTGTTCTTCCTCCTGCTGGCCGAGATCATTCCGCCCACGTCGCTGACGGTGCCGCTGCTGGGAAAGTATCTGCTCTTCACCATGATGCTGGTCACGCTCTCTGTCGTGGTCACCATTGCCGTGCTCAATGTGAATTTTAG

Seq C2 exon

ATCCCCTGTCACGCATCGCATGGCACCGTGGGTGCAGCGCCTCTTCATCCAGATCCTGCCCAAGCTGCTCTGCATCGAGCGGCCCAAGAAGGAGGAGCCCGAGGAGGACCAGCCGCCCGAAGTGCTCACCGATGTCTATCACCTGCCGCCGGATGTGGACAAGTTTGTCAACTACGATTCGAAGCGTTTCAGCGGCGACTACGGCATTCCAG

VastDB Features

Vast-tools module Information

Secondary ID

FBgn0000036-'6-10,'6-9,7-10=AN

Average complexity

A_S

Mappability confidence:

100%=100=100%

Protein Impact

ORF disruption upon sequence exclusion

No structure available

Features