DmeEX6023982 @ dm6

Exon Skipping

Gene

Description

The gene Darkener of apricot is referred to in FlyBase by the symbol DmelDoa (CG42320, FBgn0265998). It is a protein_coding_gene from Dmel. It has 16 annotated transcripts and 16 polypeptides (11 unique). Gene sequence location is 3R:28888073..28922772. Its molecular function is described by: kinase activity; ATP binding; protein kinase activity; protein serine/threonine kinase activity. It is involved in the biological process described with 14 unique terms, many of which group under: multicellular organism development; visual system development; negative regulation of biological process; positive regulation of immune system process; embryo development. 88 alleles are reported. The phenotypes of these alleles manifest in: intracellular organelle; cellular anatomical entity; interommatidial bristle; sex comb; extracellular matrix. The phenotypic classes of alleles include: phenotype; increased mortality; stress response defective; increased mortality during development.

Coordinates

chr3R:28920354-28920860:+

Coord C1 exon

chr3R:28920354-28920467

Coord A exon

chr3R:28920537-28920627

Coord C2 exon

chr3R:28920690-28920860

Length

91 bp

Sequences

Splice sites

3' ss Seq

TATCTTTCTTGCTCCTTCAGTTT

3' ss Score

9.85

5' ss Seq

TTGGTGAGT

5' ss Score

9.27

Exon sequences

Seq C1 exon

TGATTACTGCATGGCTTTAAAGATTATTAAGAACGTGGAAAAGTACCGCGAAGCTGCCAAGCTGGAAATAAATGCTTTGGAAAAGATTGCCCAAAAGGATCCGCATTGTGATCA

Seq A exon

TTTGTGCGTCAAAATGATTGACTGGTTTGATTATCATGGACACATGTGTATAGTTTTTGAAATGTTGGGGCTCAGTGTTTTCGATTTTTTG

Seq C2 exon

CGAGAGAACAACTATGAGCCATACCCGCTGGACCAAGTGCGCCATATGGCCTATCAATTATGCTACTCTGTGAAATTTCTACATGACAATCGTTTAACGCACACAGATCTCAAGCCGGAGAACATACTCTTCGTCGACTCGGATTATACTTCTCACTATAATCATAAGATT

VastDB Features

Vast-tools module Information

Secondary ID

FBgn0265998-'42-36,'42-35,43-36=AN

Average complexity

A_S

Mappability confidence:

100%=100=100%

Protein Impact

ORF disruption upon sequence exclusion

No structure available

Features

Disorder rate (Iupred):

C1=0.000 A=0.000 C2=0.000

Domain overlap (PFAM):

C1:

PF0006920=Pkinase=FE(12.1=100)

A:

PF0006920=Pkinase=FE(9.5=100)

C2:

PF0006920=Pkinase=FE(17.8=100)

Main Inclusion Isoform:

FBpp0289029

Main Skipping Isoform:

NA

Other Inclusion Isoforms:

FBpp0289020, FBpp0289021, FBpp0289022, FBpp0289023, FBpp0289025, FBpp0289026, FBpp0289027, FBpp0289028, FBpp0289030, FBpp0289031, FBpp0300822, FBpp0300823, FBpp0300824, FBpp0307567

Other Skipping Isoforms:

NA

Associated events

Conservation

Human

(hg38)

chr1:155266729-155266895

Human

(hg38)

chr15:74625802-74625968

HIGH PSI

HsaEX0015702