DmeEX6000006 @ dm6
Exon Skipping
Gene
FBgn0025836 | RhoGAP1A
Description
The gene Rho GTPase activating protein at 1A is referred to in FlyBase by the symbol DmelRhoGAP1A (CG40494, FBgn0025836). It is a protein_coding_gene from Dmel. It has 7 annotated transcripts and 7 polypeptides (4 unique). Gene sequence location is X:127449..140340. Its molecular function is described by: Rho guanyl-nucleotide exchange factor activity; GTPase activator activity. It is involved in the biological process described with: positive regulation of GTPase activity; positive regulation of Rho protein signal transduction; Golgi organization; negative regulation of cell size. 13 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.
Coordinates
chrX:134269-136075:+
Coord C1 exon
chrX:134269-134564
Coord A exon
chrX:134634-134760
Coord C2 exon
chrX:136055-136075
Length
127 bp
Sequences
Splice sites
3' ss Seq
TTTGTATTTTAATTTTAAAGGCA
3' ss Score
6.74
5' ss Seq
AAGGTGCGT
5' ss Score
9.49
Exon sequences
Seq C1 exon
ATCAAGAGCTACGAAAGCGTGTCTTCGCTAAGTTCGGAAAGTGCAAAGGCGGTGGCTTCCCAACAGTCGGCGGCAGCGGGCGGAGCTTTAGCGGAGTGTGAACCGTACTATGATAGCGTACCGCTCGACAACGGCGACGGAGAATACGTTTTTATTAAGCCCGGCCGCACCGGATCCTCATCCAGTCGCGATGATTTGTCGACGCCTGGGAGCAGCATTTTGCCTTTGCCTAATGTAGCGGATCCCGAATCTCCAGGCAGGACCTCTAACTACGTCAACATCGATTTCTTCCTTCA
Seq A exon
GCAAGGAATTGAGACGCGCTCCAGTTCGCTAGACAGTGACGGGGAGTACGAGGGTCCGCCCATATTACGCACCATTTCGCACGACGATCAAACCACAACACAAACTACTCCGGGAGCAATTCGCAAG
Seq C2 exon
AACTTAGTTTCGGCGATACTT
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0025836-'18-11,'18-10,19-11=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.598 A=0.741 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
FBpp0309061

Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0111832, FBpp0111833, FBpp0291410, FBpp0309060, FBpp0309062
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)