DmeEX0005334 @ dm6
Exon Skipping
Gene
FBgn0015773 | NetA
Description
The gene Netrin-A is referred to in FlyBase by the symbol DmelNetA (CG18657, FBgn0015773). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is X:14604012..14653928. Its molecular function is unknown. It is involved in the biological process described with 9 unique terms, many of which group under: animal organ development; cell motility; sensory organ development; tissue development; regulation of cell development. 27 alleles are reported. The phenotypes of these alleles manifest in: axon; photoreceptor cell R8 stalk; cellular anatomical entity; commissure; cell projection. The phenotypic classes of alleles include: neuroanatomy defective; oxidative stress response defective; viable; size defective; cell migration defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed at stages throughout embryogenesis.
Coordinates
chrX:14604746-14610591:-
Coord C1 exon
chrX:14610439-14610591
Coord A exon
chrX:14606483-14606548
Coord C2 exon
chrX:14604746-14605124
Length
66 bp
Sequences
Splice sites
3' ss Seq
CCATTTTATCGCCTTTTCAGAAT
3' ss Score
9.66
5' ss Seq
ACGGTAAGT
5' ss Score
11.81
Exon sequences
Seq C1 exon
AACAACCACCGCGTATGATCAACATGCTGGACACCCAGAATACCGCTCCCGAGCCGGATGAGCCCGAATCCTCTCCAGGATCTGGTGGCGACCGCAACGGCGCCGCCGGAATGGCCGCCCAGTCTCAGTACTATCGCACCGAGGGCGGCAGGG
Seq A exon
AATGCGGCAAATGCAGAGTCAGCACCAAAAGGCTAAACCTAAACAAGTTCTGCAAAAGAGACTACG
Seq C2 exon
CAATAATGGCCAAAGTAATTGGTCGCGATACGAGCAGCGAGGCGGTCAGCAGGGAAGTTCAACGGCGCGCAATGGATCCCGACGTGGCGGACTACGAAATGGATCAGGTGCAGCCGGGATCGGCCCGATCTCCGATCACGGGGGTGTACGAGTTTCAGGCGGCGGACTATCCCAATCCCAATCCCAATCCCAGAGGCAGCGAAATGGAGCGCTTCGATCTGCAGATCCAGGCCGTCTTCAAGCGCAGCAGGCCAGGCGAAAGCAGCGGCGCGGGGAACGTGTACGGAATGCCGAATACAACCCTAAAACGCGGTCCTATGACCTGGATCATACCGACTAAGGACCTGGAGTGCCGCTGCCCCAGGATCAGAGTAAACAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0015773-'6-6,'6-5,8-6
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.737 A=0.333 C2=0.695
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0175916=NTR=PU(60.6=49.6)
Main Inclusion Isoform:
FBpp0073759
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0300656, FBpp0311922
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
GATCAACATGCTGGACACCCA
R:
CTGCTCGTATCGCGACCAATT
Band lengths:
174-240
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)