DmeEX6011627 @ dm6

Exon Skipping

Gene

Description

The gene Patronin is referred to in FlyBase by the symbol DmelPatronin (CG33130, FBgn0263197). It is a protein_coding_gene from Dmel. It has 14 annotated transcripts and 14 polypeptides (13 unique). Gene sequence location is 2R:17519024..17535866. Its molecular function is described by: microtubule minus-end binding; spectrin binding; calmodulin binding; microtubule binding. It is involved in the biological process described with 6 unique terms, many of which group under: developmental process; cytoskeleton organization; negative regulation of cellular process; plasma membrane bounded cell projection organization; microtubule-based process. 36 alleles are reported. The phenotypes of these alleles manifest in: cellular anatomical entity; intracellular non-membrane-bounded organelle; cytoskeleton; organelle; plasma membrane bounded cell projection. The phenotypic classes of alleles include: viable; size defective; increased mortality; phenotype.

Coordinates

chr2R:17531211-17531802:-

Coord C1 exon

chr2R:17531714-17531802

Coord A exon

chr2R:17531518-17531653

Coord C2 exon

chr2R:17531211-17531461

Length

136 bp

Sequences

Splice sites

3' ss Seq

ATTTCCTTTCTACCTTGCAGAAT

3' ss Score

10.93

5' ss Seq

AATGTAAGT

5' ss Score

8.62

Exon sequences

Seq C1 exon

AACGCCCACATGTCTGTGATAGAATCGCTGATGGTTTTGTATGCGAAGGAAATATCATCGGGTGACCGCGTCATGGCGGCCATACGAAG

Seq A exon

AATATCTGGCAACAACTATCAGGCACCCACTGGCCAGTCCTACGAGCAAGCTCTGCTGGGCTGGATTTCACATGCTTGCGCCGCTCTGAAAAAGCGCATTATCAAGGAGGTGGACGCTGGGCTGCCCGACGATAAT

Seq C2 exon

GGTTCACGTCTGCAGACGCCGGATATACCACCTGTAAGGGACTTCCAGGATCTGTGCGATGGCATCTGTTTGGCGCTGCTCATCTCCTACTACTGCCCAAAGGTGGTGCCGTGGACGAGTGTGCGGATTAACTATTTGCCCGCCGTCGAGGACTCTATTCACAACATCCTGCTGGTCTGCAATTTCTCGCAGAAGCATCTGCCCTACACCGTGATGCATATGACGCCCGAGGATGTGACCTACATGCGCGG

VastDB Features

Vast-tools module Information

Secondary ID

FBgn0263197-'14-6,'14-5,15-6=AN

Average complexity

A_S

Mappability confidence:

100%=100=100%

Protein Impact

ORF disruption upon sequence exclusion

No structure available

Features

Disorder rate (Iupred):

C1=0.000 A=0.020 C2=0.046

Domain overlap (PFAM):

C1:

NO

A:

PF119713=CAMSAP_CH=PU(0.1=0.0)

C2:

PF119713=CAMSAP_CH=PD(97.6=97.6)

Main Inclusion Isoform:

FBpp0304550

Main Skipping Isoform:

NA

Other Inclusion Isoforms:

FBpp0086104, FBpp0086105, FBpp0086106, FBpp0271954, FBpp0271955, FBpp0289830, FBpp0304551, FBpp0304552, FBpp0304553, FBpp0304554, FBpp0304555, FBpp0304556

Other Skipping Isoforms:

NA

Associated events

Conservation

Human

(hg38)

chr1:200807376-200807537

HIGH PSI

HsaEX0012289

(CAMSAP2)

Human

(hg38)