Special

DmeEX6012463 @ dm6

Exon Skipping

Gene
FBgn0034598 | CG4266
Description
This gene is referred to in FlyBase by the symbol DmelCG4266 (FBgn0034598). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 2R:21161713..21168659. Its molecular function is described by: mRNA binding; nucleic acid binding. The biological processes in which it is involved are not known. 13 alleles are reported. The phenotypes of these alleles manifest in: chaeta; mesothoracic tergum. The phenotypic classes of alleles include: viable; visible; body color defective; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages.
Coordinates
chr2R:21165559-21167042:-
Coord C1 exon
chr2R:21166890-21167042
Coord A exon
chr2R:21166730-21166834
Coord C2 exon
chr2R:21165559-21165874
Length
105 bp
Sequences
Splice sites
3' ss Seq
TCATTATGATTTGCTTTCAGGGA
3' ss Score
9.02
5' ss Seq
GAGGTATAC
5' ss Score
6.64
Exon sequences
Seq C1 exon
GAGAAGAAGATCAAGCAGCTGCTAAACAATCCGAATGTGCTGCGGCAGCTCCATACGCTGCAGAACTTCCAAAATTTGAAGCCGCAGGAGGAGAACCAGAAGCATCGCTATCAGGACGAGGCACTGCAGCAGCATTTCCAGAACGTAATGAAG
Seq A exon
GGAAATGCTGGTATGCCGCCGGGCATGGGCATGGGCATGAACATGAACGACAGCATGGACCTTAACAAGGATGTCGAGTTCATATCGGAGCAACAGACCATAGAG
Seq C2 exon
GTGATCAATCTGGATGGTGGCGATTCCCGCAGCCCGACGCCCGACCGTGATCGCTACAAGCGCAGTCGCCGGAACAGTCGCAGCCGGACGAGATCTCCGCGAGGACGTGGCGCCGGAGGAGGCACGGGCAACGATCGACGTCGGCGTGGCACTCGTTCCCGATCGCGCAGCCGATCACCACGGTCCAGCCGGCGACGCGGATCAAGGGACCGGGATCGCATGGATCGTAGCAATCGAGACAAGGAACGCGATCGGGAACACGAGCGTGAGCGGCGCAAGAAGGGATTGCCCGACATCAAAAAGGAGCATCTCAGTG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0034598-'5-4,'5-3,6-4=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact

Alternative protein isoforms (Ref)

No structure available
Features
Disorder rate (Iupred):
  C1=0.903 A=0.900 C2=0.953
Domain overlap (PFAM):

C1:
NO
A:
NO
C2:
NO


Main Inclusion Isoform:
FBpp0112013


Main Skipping Isoform:
NA


Other Inclusion Isoforms:
FBpp0071554, FBpp0302570, FBpp0309673


Other Skipping Isoforms:
NA
Associated events
Primers PCR
Suggestions for RT-PCR validation
F:
GCAGCAGCATTTCCAGAACGT
R:
CTACGATCCATGCGATCCCG
Band lengths:
258-363
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)