DmeEX6013051 @ dm6

Exon Skipping

Gene

Description

This gene is referred to in FlyBase by the symbol DmelCG3530 (FBgn0028497). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2R:23389009..23396680. Its molecular function is described by: metal ion binding; phosphatidylinositol-3-phosphatase activity; protein tyrosine phosphatase activity; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity. It is involved in the biological process described with: phosphatidylinositol dephosphorylation; mitotic cell cycle; regulation of autophagy. 8 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; extracellular matrix; embryonic/larval fat body; trichogen cell; wing. The phenotypic classes of alleles include: planar polarity defective; visible; viable; female semi-sterile; exocytosis defective; flightless. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 and 18-24 hour embryonic stages.

Coordinates

chr2R:23389719-23390817:-

Coord C1 exon

chr2R:23390305-23390817

Coord A exon

chr2R:23390006-23390248

Coord C2 exon

chr2R:23389719-23389941

Length

243 bp

Sequences

Splice sites

3' ss Seq

ACTATGCGCTTCTCACACAGGTT

3' ss Score

8.08

5' ss Seq

CAAGTGCGT

5' ss Score

6.68

Exon sequences

Seq C1 exon

GCCGTGGACAAGGGCGTCTCGGTGGTGGTCCACTGCTCCGACGGCTGGGACCGCACGGCCCAGGTCTGTTCACTGGCGCAGCTGATGCTGAACCCCTACTACCGAACCATCAAGGGCTTCCAGGCGCTAATCGAGAAGGACTGGCTGGCATTCGGGCACAAGTTCAGCGAGCGCTGCGGTCACATCCAGACGGATGCCCGCGAGGTGTCGCCGATCTTCACACAGTTCCTGGACTGTACCTGGCAGCTAATGTCGCAGCGCAGCGAGGCCTTCGAGTTCAACGAGCGGTTCCTGCTCATCCTGCACGACCATGTGCACTCATGTCAATTCGGCACCTTCGTGGGCAACTGCGAGAAGGATCGCTTGGACCTAAAGCTGGCCGAGCGCACCTTCTCGCTGTGGGGCTATATGGCCAATCACCTGAACGAGTATATCAACCCGCTGTACAAACCAAATGTAGACGAGGCCATTAAGGCCAACCTGGCACCGCAGTGCATCAA

Seq A exon

GTTCTGGCGCGGCATGTACAGTCGCTTCGAGAGCGGCATTCATCCGCGGGAGCCACTGGGCGACGTGCTGCTCGATAGCAAGGAGCACTGCAACTCGCTGGAGGACCACGTGCAGCATCTGACCAAGCGCATAGCCAGCTTCAAGAACTACATTTCCAAGTCGGCCAAGAAACTGCAAGACGCCACCAGCGCCCCTGGCAAAGTGAACAAGGAGCTCTCCAGCAACGAGATCAATGACAACAA

Seq C2 exon

ATACAACTACGATAAGAAGCTTAGCGAACTGTCTGCCGCCGACGACGATCATCCGCTGAAGGCCAGCAACATGTCCTTCGCCAGTCTGTCGCTGAGCGCGGAACAATCCAGTCCGCCGCAGGCGCTGCCCGAGGAGATCAACTCCGTGGCCGTAGACTGGAAGCCCATGCGCAACGTAACCACCTGCTCCTGCTCCACGCCCTTCGATCAGTTCAGCAAAAAG

VastDB Features

Vast-tools module Information

Secondary ID

FBgn0028497-'11-11,'11-9,12-11=AN

Average complexity

A_S

Mappability confidence:

100%=100=100%

Protein Impact

Alternative protein isoforms (Ref)

No structure available

Features