DmeEX0005645 @ dm6
Exon Skipping
Gene
FBgn0263197 | Patronin
Description
The gene Patronin is referred to in FlyBase by the symbol DmelPatronin (CG33130, FBgn0263197). It is a protein_coding_gene from Dmel. It has 14 annotated transcripts and 14 polypeptides (13 unique). Gene sequence location is 2R:17519024..17535866. Its molecular function is described by: microtubule minus-end binding; spectrin binding; calmodulin binding; microtubule binding. It is involved in the biological process described with 6 unique terms, many of which group under: developmental process; cytoskeleton organization; negative regulation of cellular process; plasma membrane bounded cell projection organization; microtubule-based process. 36 alleles are reported. The phenotypes of these alleles manifest in: cellular anatomical entity; intracellular non-membrane-bounded organelle; cytoskeleton; organelle; plasma membrane bounded cell projection. The phenotypic classes of alleles include: viable; size defective; increased mortality; phenotype.
Coordinates
chr2R:17522853-17524282:-
Coord C1 exon
chr2R:17524084-17524282
Coord A exon
chr2R:17523824-17523898
Coord C2 exon
chr2R:17522853-17522960
Length
75 bp
Sequences
Splice sites
3' ss Seq
TTTGAATTTGAACTTAACAGGCT
3' ss Score
3.85
5' ss Seq
AAGGTAATT
5' ss Score
8.83
Exon sequences
Seq C1 exon
GGTAAAACCCTGGATCGGCCCGATCTGCACGTGAAGCTGCAATCGCATTCATCCACCTCAACGACCCCACGACTGAGGCAGCAGCGCACCACGCGTCCCAGGCCTAAGACAATTCACGTGGACGATGCCAGCGTGGACATCAGCGAGGCTTCAAGCATCTCTAGTCGGGGCAAAAAAGGCTCAAGCTCGAATCTAACCG
Seq A exon
GCTACGGTCAACTAAGCTCAAATTCAATGAAAAGAGATTACTACAGGGGCTCCCAAGACTCCCTCACTGTAAAAG
Seq C2 exon
AGCCAGCCGGCGTAGAAAGGGGCCGCACTCTGTCGCGTATCTCCGTCGCTAAGGGCAGCACGCTTAATTTCCGGGGCCGAAAGTCCAATTCGCTAATGAATCTGTGCG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0263197_MULTIEX1-1/4=C1-3
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=0.904 C2=0.351
Domain overlap (PFAM):
C1:
PF086836=CAMSAP_CKK=PU(0.8=1.5)
A:
PF086836=CAMSAP_CKK=PU(0.8=3.8)
C2:
PF086836=CAMSAP_CKK=PU(0.8=2.7)
Main Inclusion Isoform:
FBpp0304556
Main Skipping Isoform:
FBpp0304554
Other Inclusion Isoforms:
FBpp0086106, FBpp0271954, FBpp0289830, FBpp0304550, FBpp0304551
Other Skipping Isoforms:
FBpp0304555
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
AATTCACGTGGACGATGCCAG
R:
GACTTTCGGCCCCGGAAATTA
Band lengths:
174-249
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)