Special

DmeEX0009778 @ dm6

Exon Skipping

Gene
Description
The gene swiss cheese is referred to in FlyBase by the symbol Dmelsws (CG2212, FBgn0003656). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is X:7956820..7968236. Its molecular function is described by: lysophospholipase activity; protein binding; protein kinase A catalytic subunit binding. It is involved in the biological process described with 11 unique terms, many of which group under: multicellular organismal process; programmed cell death; cellular lipid metabolic process; apoptotic process; cellular process. 32 alleles are reported. The phenotypes of these alleles manifest in: cellular anatomical entity; cytoplasm; organelle; adult sense organ; cell body rind of lamina. The phenotypic classes of alleles include: short lived; phenotype; phototaxis defective; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during late pupal stages, in stages of adults of both sexes.
Coordinates
chrX:7958271-7961363:-
Coord C1 exon
chrX:7961177-7961363
Coord A exon
chrX:7959996-7960112
Coord C2 exon
chrX:7958271-7958482
Length
117 bp
Sequences
Splice sites
3' ss Seq
CCGTTGATTTTAAATACCAGGAT
3' ss Score
5.84
5' ss Seq
CAGGTAATT
5' ss Score
8.55
Exon sequences
Seq C1 exon
AAAATGACGAAATGGTTCCTACAACTACTTGACCTCACCTACCCGATCACATCGATGTTCTCCGGACGAGAGTTCAACAAGACGATCCACGACACTTTCGGGGACGTGAGCATCGAGGACCTGTGGATACCCTACTTCACCCTCACCACCGACATAACCGCCAGTTGCCATCGCATTCACACCAATG
Seq A exon
GATCTCTGTGGCGTTACGTACGCTCCTCCATGTCGCTCAGTGGCTACATGCCGCCGTTATGCGATCCTAAAGATGGGCACCTCTTGCTGGATGGCGGCTATGTGAATAATCTGCCAG
Seq C2 exon
CCGATGTGATGCATAATCTTGGAGCTGCTCACATAATCGCCATCGATGTGGGATCCCAGGATGACACTGACCTGACCAACTATGGCGACGACCTAAGCGGTTGGTGGCTGCTCTACAAGAAATGGAATCCCTTCACATCGCCTGTGAAGGTGCCCGACTTGCCGGACATCCAATCCCGACTAGCCTATGTGTCCTGCGTACGCCAACTAGAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0003656_MULTIEX1-1/2=C1-C2
Average complexity
ME(1-2[99=100])
Mappability confidence:
100%=100=100%
Protein Impact

Alternative protein isoforms (Ref)

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):

C1:
PF0173417=Patatin=FE(37.1=100)
A:
PF0173417=Patatin=FE(23.4=100)
C2:
PF0173417=Patatin=PD(2.4=5.6)


Main Inclusion Isoform:
FBpp0071077


Main Skipping Isoform:
FBpp0290889


Other Inclusion Isoforms:
NA


Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
GACCTCACCTACCCGATCACA
R:
TAGGTCGTCGCCATAGTTGGT
Band lengths:
252-369
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)