DmeEX0009884 @ dm6
Exon Skipping
Gene
FBgn0033636 | tou
Description
The gene toutatis is referred to in FlyBase by the symbol Dmel ou (CG10897, FBgn0033636). It is a protein_coding_gene from Dmel. It has 6 annotated transcripts and 6 polypeptides (5 unique). Gene sequence location is 2R:11577485..11616045. Its molecular function is described by: protein binding; transcription factor binding; DNA binding. It is involved in the biological process described with: ATP-dependent chromatin remodeling; nervous system development; positive regulation of transcription by RNA polymerase II. 67 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; wing; dorsocentral bristle; wing vein L5; scutellar bristle. The phenotypic classes of alleles include: fertile; visible; partially lethal; lethal; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages.
Coordinates
chr2R:11587097-11588127:-
Coord C1 exon
chr2R:11587771-11588127
Coord A exon
chr2R:11587646-11587711
Coord C2 exon
chr2R:11587097-11587138
Length
66 bp
Sequences
Splice sites
3' ss Seq
ATGCGAACTCGTATTTTTAGGAG
3' ss Score
5.7
5' ss Seq
CAGGTTAGT
5' ss Score
8.02
Exon sequences
Seq C1 exon
ATCCTGGAGCAGCAGCCATCGAATCTAAGTCGTGAAAACTTTAGTTTTTCCGCGCGAGCCATTGTTGGTTCATTCCTGCAGCCTGCACCACCGCCGTACGCCAATGATGGCGAGTACATACGGATGACGGACGAGGACGTGGCCAAGCGGTTAGAGGATCTGAAGGTCTTCACCCGCCAGACTCTTAACGTGGAACAGCGAATTGAGATCGCCAAGCAACAGCAGGCGATGCGTGATGCTAAGAAGCTGCAAAAGGAAGAATTGGCCAGAAATAAGGAGAAGGCGCGACAGGAGAAGAACTCCAAGTTGGAGCAGCAGCGCAAGGACAAGGAGCTCAAGAATCAGCAGGCTGTTGAG
Seq A exon
GAGCGCAAAAAGCGTCAGGAGGAGCTAGATCGCCTTAAGCAAGAGGAATTGCTTAAGAAGCAACAG
Seq C2 exon
GAACTACAGAAACAAAAAGAGATGCTGTTGGCTGCCGAAATG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0033636_MULTIEX1-1/2=C1-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.563 A=0.848 C2=0.607
Domain overlap (PFAM):
C1:
PF0142914=MBD=PD(30.3=19.3)
A:
NO
C2:
NO
Main Inclusion Isoform:
FBpp0305283
Main Skipping Isoform:
FBpp0305284
Other Inclusion Isoforms:
FBpp0087193, FBpp0111979
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
GGCGATGCGTGATGCTAAGAA
R:
CATTTCGGCAGCCAACAGC
Band lengths:
175-241
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)