DmeEX0005308 @ dm6
Exon Skipping
Gene
FBgn0259111 | Ndae1
Description
The gene Na[+]-driven anion exchanger 1 is referred to in FlyBase by the symbol DmelNdae1 (CG42253, FBgn0259111). It is a protein_coding_gene from Dmel. It has 11 annotated transcripts and 11 polypeptides (10 unique). Gene sequence location is 2L:7223328..7249343. Its molecular function is described by: inorganic anion exchanger activity; anion:anion antiporter activity; sodium:bicarbonate symporter activity. It is involved in the biological process described with 6 unique terms, many of which group under: transport; establishment of localization; ion transmembrane transport; localization; inorganic ion transmembrane transport. 16 alleles are reported. The phenotype of these alleles manifest in: imaginal disc. The phenotypic classes of alleles include: viable; lethal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 18-24 hour embryonic stages.
Coordinates
chr2L:7237687-7249343:-
Coord C1 exon
chr2L:7248829-7249343
Coord A exon
chr2L:7244974-7245083
Coord C2 exon
chr2L:7237687-7237790
Length
110 bp
Sequences
Splice sites
3' ss Seq
TTTTCGGGCGTACTTTCCAGGTT
3' ss Score
7.96
5' ss Seq
CAGGTAAAT
5' ss Score
8.76
Exon sequences
Seq C1 exon
GTCAAACCATAACCAAGCCAATTAATCCAAAAATATGGAAATCAATTGTTAAACCACCTAAAACGAAAAATTGTGAAATTTGTTAAACACTCTAAACGTGCATTTAATACATAAATAACCATACGAAATACGTATATTCAGCTCTACAAATAAATCCTACTTTAAAGGAAAAGCTTGTTTTACCCTTATTTTAAGGAGCAATACGCCACGATTAAATCGATACGAAATTTAAAAATAAATCAATCAATCTCCGCAAATTTCCACAACCAAACACTGCCAATGTGAACCCATCTATTTCAAAAAAGTAACCCGCCTAAAGATAACGACACTCGAAAATAACCGTTAACGAGCATTTAAGAGGTCACAACAGTATTCTCAACTTTAACTGTAACAGTTACTAGCGGTAACTGGGTCAGTAGGCAGAGCCGAAGTAACGCCCCCCATCGAGGGCTTCCTCATCCACCTTCTGCATCCTTCTTGGCTCCCATCCTTTCGGTGTG
Seq A exon
GTTGGAGATCACAACTGAAATCAAGGATTCAGGATGCCACAGCAGGCGCAGCTGAAACACATCCACGGACATGGCCGATTGCCCAGAGTGATAGCCACTGAAAGCAGCAG
Seq C2 exon
ACCTTGGACCATGAACTCCTCCAGCGGCGATGACGAGGCGCCGAAGGATCCGCGCACTGGCGGCGAGGATTTTACGCAACAATTTACAGAGAATGATTTCGAGG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0259111_CASSETTE2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. ATG)
No structure available
Features
Disorder rate (Iupred):
C1=NA A=1.000 C2=0.972
Domain overlap (PFAM):
C1:
NA
A:
NO
C2:
NO
Main Inclusion Isoform:
FBpp0304050
Main Skipping Isoform:
FBpp0288814
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg19)
No conservation detected
Mouse
(mm9)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AACACTGCCAATGTGAACCCA
R:
GCTGGAGGAGTTCATGGTCCA
Band lengths:
256-366
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)