DmeEX6009761 @ dm6
Exon Skipping
Gene
FBgn0261698 | CG42732
Description
The gene slowpoke 2 is referred to in FlyBase by the symbol DmelSLO2 (CG42732, FBgn0261698). It is a protein_coding_gene from Dmel. It has 10 annotated transcripts and 10 polypeptides (9 unique). Gene sequence location is 2R:10322195..10416996. Its molecular function is described by: calcium-activated potassium channel activity; outward rectifier potassium channel activity; intracellular sodium activated potassium channel activity. It is involved in the biological process described with: potassium ion transmembrane transport; potassium ion transport. 21 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; ganglion mother cell; trichogen cell. The phenotypic classes of alleles include: phenotype; increased mortality; increased mortality during development; some die during P-stage.
Coordinates
chr2R:10332056-10335413:-
Coord C1 exon
chr2R:10335264-10335413
Coord A exon
chr2R:10334896-10335161
Coord C2 exon
chr2R:10332056-10332367
Length
266 bp
Sequences
Splice sites
3' ss Seq
ATACAATTCCACTTCCGCAGATA
3' ss Score
7.38
5' ss Seq
CTGGTGGGT
5' ss Score
6.29
Exon sequences
Seq C1 exon
GGAGGGCCAGCAGAGTCCGGAGGAATGGCACCGTCTGTACGGCAAGTGTTCCGGAAACGAGATCTACCACATCGTCCTGGGCGACAGTCGATTCTTTGGCGAGTACGAGGGCAAGAGCTTCACCTACGCCAGCTTCCATTCGCATCGCAA
Seq A exon
ATATGGAGTGGCCCTGGTGGGCGTGCGACCGGCGGAGCTGCCGGAATTCTACGAGGAAACCATTCTATTGAATCCCGGACCCAGGCACATTATGAAAAAGGATGACACGTGCTATTACATGAGCATCACCAAGGAAGAGAATTCCGCATTTGTCGTTAATCAAAATCAAACATCGGACCCCACGGCAGCTGCCAAGGAGGGGAGCGGGACAGGGGGCGGAGGCGGTGCCTCCTCATCCGCCTCCCACCACCACACTGCTGCAACTG
Seq C2 exon
CTAGCGAAAATCCGACGGCTGTGATAATCTCGGACTCTAGGCAGAACCTCAAGGACACGACGGTGACCCAGACGGCGGCAACGATAACCACAACGACTCTGCCGCCACCGCCCCAGACGATGGGATCCCCCAGCATGGCGGGCGGATCGGGTGGATGTGGTGGAGGCGGCCTCGGCTTGGGCAGTGCCCACAGCATGGGCACCTCGCTCAGTATCACCCCAGCCACACTGACCACCACGGGCAATCACCTGGATGTGCCCTTTGCCAACAATCCCAACCTGCTCAGCCCAGATGTGCTCAACCAGCGGAGGG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0261698-'22-30,'22-27,23-30=AN
Average complexity
A_C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.078 A=0.465 C2=0.999
Domain overlap (PFAM):
C1:
PF0349313=BK_channel_a=FE(47.2=100)
A:
PF0349313=BK_channel_a=PD(8.5=10.0)
C2:
NO
Main Inclusion Isoform:
FBpp0292201
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0292199, FBpp0292200, FBpp0292202, FBpp0297088, FBpp0302905, FBpp0302908, FBpp0302970, FBpp0303466
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
CAAGAGCTTCACCTACGCCAG
R:
AAGGGCACATCCAGGTGATTG
Band lengths:
301-567
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)