DmeEX0003483 @ dm6
Exon Skipping
Gene
FBgn0020503 | CLIP-190
Description
The gene Cytoplasmic linker protein 190 is referred to in FlyBase by the symbol DmelCLIP-190 (CG5020, FBgn0020503). It is a protein_coding_gene from Dmel. It has 16 annotated transcripts and 16 polypeptides (15 unique). Gene sequence location is 2L:17384700..17409698. Its molecular function is described by: microtubule binding; myosin VI heavy chain binding; actin binding; protein binding; microtubule plus-end binding. It is involved in the biological process described with: nuclear migration; cytoplasmic microtubule organization; cellularization; establishment of mitotic spindle orientation. 21 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 18-24 hour embryonic stages, at stages throughout the pupal period, in adult male stages.
Coordinates
chr2L:17401519-17404840:+
Coord C1 exon
chr2L:17401519-17401581
Coord A exon
chr2L:17402375-17402485
Coord C2 exon
chr2L:17404730-17404840
Length
111 bp
Sequences
Splice sites
3' ss Seq
TCGATCGATCGACATTGTAGGAT
3' ss Score
3.49
5' ss Seq
GAGGTAATT
5' ss Score
8.88
Exon sequences
Seq C1 exon
CGCAAGTCGAGCACGCCCGTTAAGCCAATTTTAGCGACGCCGAAAAGCCAATTTTCCATGCAG
Seq A exon
GATCTGCTGCGCGAGAAGCAACAACATGTGGAGAAGCTGATGGTGGAGCGCGACCTGGACCGCGAGGATGCCCAGAACCAGGCGCTGCAGCTGCAGAAGAACATCAACGAG
Seq C2 exon
CTAAAAGCAAGAATCGTTGAATTGGAGTCGGCATTGGACAATGAACGAAAGAAAACTGAAGAATTGCAGTGCTCCATAGACGAAGCCCAGTTTTGTGGCGATGAATTGAAT
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0020503-'13-29,'13-27,15-29
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.660 A=0.589 C2=0.213
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
FBpp0080529
Main Skipping Isoform:
FBpp0304727
Other Inclusion Isoforms:
FBpp0080528, FBpp0080530, FBpp0288701, FBpp0290655, FBpp0290656, FBpp0290657, FBpp0304724, FBpp0304726
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
AAGTCGAGCACGCCCGTTAA
R:
TTCAATTCATCGCCACAAAACTGG
Band lengths:
170-281
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)