DmeEX0002408 @ dm6
Exon Skipping
Gene
FBgn0034598 | CG4266
Description
This gene is referred to in FlyBase by the symbol DmelCG4266 (FBgn0034598). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 2R:21161713..21168659. Its molecular function is described by: mRNA binding; nucleic acid binding. The biological processes in which it is involved are not known. 13 alleles are reported. The phenotypes of these alleles manifest in: chaeta; mesothoracic tergum. The phenotypic classes of alleles include: viable; visible; body color defective; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages.
Coordinates
chr2R:21164300-21166834:-
Coord C1 exon
chr2R:21166730-21166834
Coord A exon
chr2R:21165559-21165874
Coord C2 exon
chr2R:21164300-21165043
Length
316 bp
Sequences
Splice sites
3' ss Seq
AACACTCCCATCTCCGATAGGTG
3' ss Score
8.6
5' ss Seq
GTGGTAACT
5' ss Score
5.08
Exon sequences
Seq C1 exon
GGAAATGCTGGTATGCCGCCGGGCATGGGCATGGGCATGAACATGAACGACAGCATGGACCTTAACAAGGATGTCGAGTTCATATCGGAGCAACAGACCATAGAG
Seq A exon
GTGATCAATCTGGATGGTGGCGATTCCCGCAGCCCGACGCCCGACCGTGATCGCTACAAGCGCAGTCGCCGGAACAGTCGCAGCCGGACGAGATCTCCGCGAGGACGTGGCGCCGGAGGAGGCACGGGCAACGATCGACGTCGGCGTGGCACTCGTTCCCGATCGCGCAGCCGATCACCACGGTCCAGCCGGCGACGCGGATCAAGGGACCGGGATCGCATGGATCGTAGCAATCGAGACAAGGAACGCGATCGGGAACACGAGCGTGAGCGGCGCAAGAAGGGATTGCCCGACATCAAAAAGGAGCATCTCAGTG
Seq C2 exon
TATGCAGCACTACGCTGTGGGTGGGCCACCTGTCTAAGCTTGTTTACCAGGAGGAGCTGTCCGATACCTTTGGCGAATATGGCGATATAGTGAGCATCGATCAGATTGTGCCGCGTGGATGCGCTTTTATTGTAATGAACCGACGCCAAGACGCCCACAAGGCGATGCAAGCTCTGAAGAACCACAAGCTGCAGGGACGAGCCATCACCATTTCATGGGCCGCCGGCAAGGGTGTGAAAAGCAAGGAGTGGAAGGACTACTGGGACCTCGAATTGGGTGTTACTTACATTCCTTGGTCCAAACTCAGTTCGGATACGGACTTCGACGCGCTGGAGGAGGGTGGTATGTTCGACGAAGATACTATGCCCATCCAAATGAAGCAGAAGATTAACCAGGCCAAGAATGCTGCCAAGGAGCACAAGGGTGCATCCATTGCGGAGGCAGCTGGTGCGCCAAGTGTTGGTGTTCCACCGCCAAATCTGATATTTGGTATCGATACA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0034598_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.900 A=0.953 C2=0.557
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0007617=RRM_1=WD(100=26.1)
Main Inclusion Isoform:
FBpp0112013
Main Skipping Isoform:
FBpp0302570
Other Inclusion Isoforms:
FBpp0071554, FBpp0309673
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
GCATGGGCATGAACATGAACG
R:
CGAGGTCCCAGTAGTCCTTCC
Band lengths:
347-663
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)