DmeEX0003803 @ dm6
Exon Skipping
Gene
FBgn0035533 | Cip4
Description
The gene Cdc42-interacting protein 4 is referred to in FlyBase by the symbol DmelCip4 (CG15015, FBgn0035533). It is a protein_coding_gene from Dmel. It has 12 annotated transcripts and 12 polypeptides (10 unique). Gene sequence location is 3L:4322491..4364102. Its molecular function is described by: GTPase activating protein binding; lipid binding; phospholipid binding; protein binding. It is involved in the biological process described with 13 unique terms, many of which group under: macromolecule localization; plasma membrane organization; membrane organization; mesoderm development; germ cell development. 36 alleles are reported. The phenotypes of these alleles manifest in: multicellular structure; organism; cell junction; cellular anatomical entity; integumentary system. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during early pupal stages.
Coordinates
chr3L:4327773-4338182:-
Coord C1 exon
chr3L:4338067-4338182
Coord A exon
chr3L:4336269-4336319
Coord C2 exon
chr3L:4327773-4327917
Length
51 bp
Sequences
Splice sites
3' ss Seq
CCTCTTTTTTTCTCTTGCAGGCG
3' ss Score
13.33
5' ss Seq
TGAGTAAGC
5' ss Score
5.78
Exon sequences
Seq C1 exon
GATCAAAACGAGAATCTGGCGATACACACAAACAGAGGCATCGATGCTCTGGACAAGTTTGCCAACTTCTTACGCGATCGAGTGGCCATAGAAACGGAATATGCCGGCAAATTAAG
Seq A exon
GCGCCTAGTGAAAAACTACCAGCCCAAAAAGAAGGAGGAGGAAGACAATGA
Seq C2 exon
ATTCACATCGGTGCAAGCGTTCCGCAATCTGCTCAAGGAGGTGGGCGATCTGGCGGGACAGCGCGAGGTGGTGTCCGAGTCCCTGCAGCTGCAGATCATTGCGGGAGTGACGCTTCTGTCCAAGACATTGCGCGAGGAACGCAAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0035533-'12-9,'12-7,13-9
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.631 C2=0.020
Domain overlap (PFAM):
C1:
PF0061118=FCH=FE(41.3=100)
A:
PF0061118=FCH=FE(18.5=100)
C2:
PF0061118=FCH=PD(30.4=57.1),PF0157614=Myosin_tail_1=PU(5.8=16.3)
Main Inclusion Isoform:
FBpp0112051

Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0073195, FBpp0297231, FBpp0297232, FBpp0297233, FBpp0297491, FBpp0297492, FBpp0300521, FBpp0300522, FBpp0305747, FBpp0305748
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
TCGAGTGGCCATAGAAACGGA
R:
CACTCCCGCAATGATCTGCAG
Band lengths:
148-199
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)