DmeEX0006362 @ dm6
Exon Skipping
Gene
FBgn0040285 | Scamp
Description
The gene Scamp is referred to in FlyBase by the symbol DmelScamp (CG9195, FBgn0040285). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is X:15446179..15449883. Its molecular function is unknown. It is involved in the biological process described with: neuromuscular synaptic transmission; synaptic vesicle exocytosis; protein transport; long-term memory. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; locomotor behavior defective; memory defective; heat stress response defective; short lived; fertile. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during early pupal stages.
Coordinates
chrX:15447895-15449508:-
Coord C1 exon
chrX:15449281-15449508
Coord A exon
chrX:15448379-15448580
Coord C2 exon
chrX:15447895-15448024
Length
202 bp
Sequences
Splice sites
3' ss Seq
ATGATTTTCATTGTATCCAGCGC
3' ss Score
6.04
5' ss Seq
TTTGTGAGT
5' ss Score
5.91
Exon sequences
Seq C1 exon
GACCCCGCCATCCAGCAGGCACGACGACTCCAGAGCGGCGCCGCCCTTGTCTCTCTTGAGGATTACAATCCATTCGAGGAGCAGGCCAAGCCGCAGCTGCAGATCAACTCAACGAACACGGCGGCGGTGGTCCAGCCGCTATCGCAGAACATTCCGCCCCCGCAGACCAGTTCCCTGGGCGCCTCGGCGCCTAGCACCAGCATACAGATCACCTCGGAGGAGCTGCAG
Seq A exon
CGCCGGCAGGAGGAGTTGGACCGCAAGGCCGCCGAACTGGACCGCCGCGAGCAGCAGCTACAGGGCAATGTGCCGCAGCTGAACAACTGGCCACCGCTGCCGGATAACTTTTGTGTAAAGCCGTGCTTCTACCAGGACTTCGAGGTGGAGATACCGCCCGAGTTCCAGAAACTGGTCAAGCGATTGTATTACATTTGGATTT
Seq C2 exon
TTTACACCATGACGTTGTTGGCCAACGTGATAGGCGGTCTAATTTTGCTGTTCCACGCTGGCGAATTCGAGACCTTCTTCCTGGCCATCTTCTACACGATGCTCTTCTCGCCCGCCTCCTATGTCTGCTG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0040285-'5-2,'5-1,8-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.898 A=0.309 C2=0.000
Domain overlap (PFAM):
C1:
PF039389=OmpH=PU(43.4=77.6),PF111013=DUF2884=PU(29.2=18.4),PF120723=DUF3552=PU(29.5=17.1)
A:
PF039389=OmpH=FE(49.3=100),PF111013=DUF2884=PD(66.7=47.1),PF120723=DUF3552=PD(65.9=42.6),PF041448=SCAMP=PU(23.3=61.8)
C2:
PF039389=OmpH=PD(5.9=18.2),PF041448=SCAMP=FE(23.9=100)
Main Inclusion Isoform:
FBpp0073895
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0304842
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
CGCCCTTGTCTCTCTTGAGGA
R:
GGCGAGAAGAGCATCGTGTAG
Band lengths:
299-501
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)