Special

DmeEX6009760 @ dm6

Exon Skipping

Gene
FBgn0261698 | CG42732
Description
The gene slowpoke 2 is referred to in FlyBase by the symbol DmelSLO2 (CG42732, FBgn0261698). It is a protein_coding_gene from Dmel. It has 10 annotated transcripts and 10 polypeptides (9 unique). Gene sequence location is 2R:10322195..10416996. Its molecular function is described by: calcium-activated potassium channel activity; outward rectifier potassium channel activity; intracellular sodium activated potassium channel activity. It is involved in the biological process described with: potassium ion transmembrane transport; potassium ion transport. 21 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; ganglion mother cell; trichogen cell. The phenotypic classes of alleles include: phenotype; increased mortality; increased mortality during development; some die during P-stage.
Coordinates
chr2R:10334896-10336468:-
Coord C1 exon
chr2R:10336328-10336468
Coord A exon
chr2R:10335264-10335413
Coord C2 exon
chr2R:10334896-10335161
Length
150 bp
Sequences
Splice sites
3' ss Seq
GTGTTTCGAACAATCCGCAGGGA
3' ss Score
7.04
5' ss Seq
CAAGTGAGT
5' ss Score
9.1
Exon sequences
Seq C1 exon
ACCTGAGCACAAGCTGCATGTGAAGTTCGCGGAGCACGTGGTCTGCGAGGACGAGTTCAAGTACGCCCTACTGGCCAACAACTGCACCTGTCCCGGCGCCAGCACACTGGTCACCCTGCTGCTCCACACATCCCGCGGACA
Seq A exon
GGAGGGCCAGCAGAGTCCGGAGGAATGGCACCGTCTGTACGGCAAGTGTTCCGGAAACGAGATCTACCACATCGTCCTGGGCGACAGTCGATTCTTTGGCGAGTACGAGGGCAAGAGCTTCACCTACGCCAGCTTCCATTCGCATCGCAA
Seq C2 exon
ATATGGAGTGGCCCTGGTGGGCGTGCGACCGGCGGAGCTGCCGGAATTCTACGAGGAAACCATTCTATTGAATCCCGGACCCAGGCACATTATGAAAAAGGATGACACGTGCTATTACATGAGCATCACCAAGGAAGAGAATTCCGCATTTGTCGTTAATCAAAATCAAACATCGGACCCCACGGCAGCTGCCAAGGAGGGGAGCGGGACAGGGGGCGGAGGCGGTGCCTCCTCATCCGCCTCCCACCACCACACTGCTGCAACTG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0261698-'21-27,'21-26,22-27=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact

Alternative protein isoforms (Ref)

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=0.078 C2=0.465
Domain overlap (PFAM):

C1:
PF0349313=BK_channel_a=PU(43.4=95.8)
A:
PF0349313=BK_channel_a=FE(47.2=100)
C2:
PF0349313=BK_channel_a=PD(8.5=10.0)


Main Inclusion Isoform:
FBpp0292199


Main Skipping Isoform:
NA


Other Inclusion Isoforms:
FBpp0292200, FBpp0292201, FBpp0292202, FBpp0297088, FBpp0302905, FBpp0302908, FBpp0302970, FBpp0303466


Other Skipping Isoforms:
NA
Associated events
Primers PCR
Suggestions for RT-PCR validation
F:
CTACTGGCCAACAACTGCACC
R:
CGTGGGGTCCGATGTTTGATT
Band lengths:
258-408
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)