Special

DmeEX6011625 @ dm6

Exon Skipping

Gene
FBgn0263197 | Patronin
Description
The gene Patronin is referred to in FlyBase by the symbol DmelPatronin (CG33130, FBgn0263197). It is a protein_coding_gene from Dmel. It has 14 annotated transcripts and 14 polypeptides (13 unique). Gene sequence location is 2R:17519024..17535866. Its molecular function is described by: microtubule minus-end binding; spectrin binding; calmodulin binding; microtubule binding. It is involved in the biological process described with 6 unique terms, many of which group under: developmental process; cytoskeleton organization; negative regulation of cellular process; plasma membrane bounded cell projection organization; microtubule-based process. 36 alleles are reported. The phenotypes of these alleles manifest in: cellular anatomical entity; intracellular non-membrane-bounded organelle; cytoskeleton; organelle; plasma membrane bounded cell projection. The phenotypic classes of alleles include: viable; size defective; increased mortality; phenotype.
Coordinates
chr2R:17531714-17535061:-
Coord C1 exon
chr2R:17534826-17535061
Coord A exon
chr2R:17531871-17532182
Coord C2 exon
chr2R:17531714-17531802
Length
312 bp
Sequences
Splice sites
3' ss Seq
TTACCATCGCTCCATTGCAGGCT
3' ss Score
8.74
5' ss Seq
ATTGTGAGT
5' ss Score
7.35
Exon sequences
Seq C1 exon
GCTCCAAGTGAAAATCACCTAAGCTGAGGAAAACTCCAAGCCACACTCACACACACACGCACTCGCTCGCACGCAGAAAAGAGACAAGTGAAAAAGGAAAAGCGGTGTGTTGTGGTCAAACATAGAGTGCGAAAAGTGCAAAAAGTGCGGAAAGTGAAGTGGCGGGCGTCGGAGAGCCGGAGTCCGTCGCAGGAAAATCCGTCAGCATGGATGTCGAAACACAGGAAATACGACAG
Seq A exon
GCTCGTCAACGTGCTTCCGTCAAATGGCTGCTCTCAAAGGCGTTCAACAATCGCGTGCCAGACAACCTGAAGGAGCCCTTCTACCGCGACCATGAGAACCAGGAGCGCCTCAAGCCGCAGATCATCGTGGAGCTGGGCAATGCCACGCTCTACTGCCAGACGCTGGCCAATCTGTACTCAGATCCCAACTACCAAAGCATGAACCACTGGTCAATAATACAGACGCTAGCGCGCAAGGGAGTTCCCGTGGCCGAATCCGCGGACATGCCCATTACCGAAACGGTATTAATTCAAACAAATCCGCTGCGAATT
Seq C2 exon
AACGCCCACATGTCTGTGATAGAATCGCTGATGGTTTTGTATGCGAAGGAAATATCATCGGGTGACCGCGTCATGGCGGCCATACGAAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0263197-'12-4,'12-3,13-4=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact

Alternative protein isoforms (Ref)

No structure available
Features
Disorder rate (Iupred):
  C1=0.600 A=0.077 C2=0.000
Domain overlap (PFAM):

C1:
NO
A:
NO
C2:
NO


Main Inclusion Isoform:
FBpp0304550


Main Skipping Isoform:
NA


Other Inclusion Isoforms:
FBpp0086104, FBpp0086105, FBpp0086106, FBpp0271954, FBpp0271955, FBpp0289830, FBpp0304551, FBpp0304552, FBpp0304553, FBpp0304554, FBpp0304555, FBpp0304556


Other Skipping Isoforms:
NA
Associated events
Conservation
Zebrafish
(danRer10)
HIGH PSI
Zebrafish
(danRer10)
HIGH PSI
Zebrafish
(danRer10)
HIGH PSI
Primers PCR
Suggestions for RT-PCR validation
F:
GTGAAAATCACCTAAGCTGAGGA
R:
CTTCGTATGGCCGCCATGAC
Band lengths:
318-630
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)