DmeEX6013747 @ dm6
Exon Skipping
Gene
FBgn0024806 | DIP2
Description
The gene DISCO Interacting Protein 2 is referred to in FlyBase by the symbol DmelDIP2 (CG7020, FBgn0024806). It is a protein_coding_gene from Dmel. It has 6 annotated transcripts and 6 polypeptides (5 unique). Gene sequence location is 3L:250229..257954. Its molecular function is described by: catalytic activity; protein binding. The biological processes in which it is involved are not known. 13 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.
Coordinates
chr3L:252539-252995:-
Coord C1 exon
chr3L:252835-252995
Coord A exon
chr3L:252694-252775
Coord C2 exon
chr3L:252539-252643
Length
82 bp
Sequences
Splice sites
3' ss Seq
AACTGTCCAAACTTCAACAGCCT
3' ss Score
4.26
5' ss Seq
AGGGTAAGT
5' ss Score
10.45
Exon sequences
Seq C1 exon
GTGTGCAAACTGCCGCAAAATTAAGCTCATCATCTGGATGTGGTATTACAGACACGGGTGTAGGACCAGCCTCTGTGATGGTTGGAAATTTAGTTCAGGGCAATCGCCTTGCTGAAGCCCATGGACGGGATGTTGGCCTAGCAGAAGATTGCGAAAGAAAG
Seq A exon
CCTCAATTGATAACAGGTGTGTTGCGTTGGCGAGCAAACACGTCCCCCGATCATATAATATTTACACTGCTGAACTCCAAGG
Seq C2 exon
GTGCCATCGCGAAAACACTGACATGCTCTGAGTTGCATAAGCGGGCAGAGAAAATAGCGGCATTGTTACAAGAACGAGGAAGAATTGAGCCAGGAGACCACGTTG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0024806-'10-13,'10-11,11-13=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.055 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0050123=AMP-binding=PU(4.4=71.4)
C2:
PF0050123=AMP-binding=FE(7.8=100)
Main Inclusion Isoform:
FBpp0072420
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0293868, FBpp0304418, FBpp0304419, FBpp0304420
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
TACAGACACGGGTGTAGGACC
R:
ATGCCGCTATTTTCTCTGCCC
Band lengths:
178-260
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)