DmeEX6016368 @ dm6
Exon Skipping
Gene
FBgn0052103 | CG32103
Description
The gene Short Calcium-binding Mitochondrial Carrier is referred to in FlyBase by the symbol DmelSCaMC (CG32103, FBgn0052103). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 3L:12402295..12414842. Its molecular function is described by: ATP transmembrane transporter activity; calcium ion binding. It is involved in the biological process described with: transmembrane transport. 15 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; male semi-fertile; male sterile. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during late pupal stages.
Coordinates
chr3L:12405002-12412272:-
Coord C1 exon
chr3L:12412185-12412272
Coord A exon
chr3L:12412011-12412122
Coord C2 exon
chr3L:12405002-12405160
Length
112 bp
Sequences
Splice sites
3' ss Seq
ACGCGTGACTTTTCTTGCAGAAT
3' ss Score
8.54
5' ss Seq
ACTGTGAGT
5' ss Score
7.94
Exon sequences
Seq C1 exon
GCAAAGTGGACTTGGAGGAGCTGATATCGGCGTTCAAGGACCTGGGCCTGGACATTGACATGGACGAGGCCAGAAATCTGCTCACCAG
Seq A exon
AATGGACAAGGATGGCAGCCTGAACATTAGCTTTAACGAGTGGCGGGACTTCATGCTCTTGGCGCCCTCAACGGACATTCATGACTTGATTAAATTTTGGCGGCACTCTACT
Seq C2 exon
TACCTCGACATTGGCGAGGATATGAACGTACCTGATGACTTCACACAGAAAGAGATGCAGACGGGCCTCTGGTGGCGACACTTGGTGGCCGGTGGCATAGCTGGAGCAGTTTCTCGGACGTGCACAGCGCCTCTGGACAGGATTAAAGTGTACTTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0052103-'9-8,'9-3,10-8=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF134991=EF-hand_7=FE(43.3=100),PF078487=PaaX=FE(48.3=100)
A:
PF134991=EF-hand_7=PD(26.9=47.4),PF078487=PaaX=PD(35.0=55.3)
C2:
PF0015322=Mito_carr=PU(36.3=62.3)
Main Inclusion Isoform:
FBpp0075714
Main Skipping Isoform:
FBpp0075715
Other Inclusion Isoforms:
FBpp0304400
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
AAGTGGACTTGGAGGAGCTGA
R:
TGCAAGTACACTTTAATCCTGTCCA
Band lengths:
243-355
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)