DmeEX6003122 @ dm6
Exon Skipping
Gene
FBgn0261570 | CG42684
Description
The gene raskol is referred to in FlyBase by the symbol Dmel
askol (CG42684, FBgn0261570). It is a protein_coding_gene from Dmel. It has 10 annotated transcripts and 10 polypeptides (9 unique). Gene sequence location is X:17710144..17752007. Its molecular function is unknown. It is involved in the biological process described with: negative regulation of Ras protein signal transduction; regulation of GTPase activity. 37 alleles are reported. The phenotypes of these alleles manifest in: border follicle cell; filamentous actin. The phenotypic classes of alleles include: cell adhesion defective; viable; behavior defective; smell perception defective; fertile; cell migration defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 06-12 hour embryonic stages.
Coordinates
chrX:17736198-17746898:+
Coord C1 exon
chrX:17736198-17736269
Coord A exon
chrX:17746571-17746691
Coord C2 exon
chrX:17746771-17746898
Length
121 bp
Sequences
Splice sites
3' ss Seq
CTACGCTTCCTTCTTTGCAGATA
3' ss Score
11.05
5' ss Seq
GAAGTAAGT
5' ss Score
9.82
Exon sequences
Seq C1 exon
GTGAGTACAAGTCGAAGACACTGCCTCGCATACATTTCGATACGGCGTTAAACGATACATCGCTGAATGAAG
Seq A exon
ATACGTCCTATGAGAAGGCGTGCCGCCGTGGATCAGCGCCCACCACGCCCATTTTGGGCAGCAAACAGCACCAGACGGAGCACAATGCCACCTCGCGTTTCACCAACTTCTTTTCCAAGAA
Seq C2 exon
ATCCAATCCTTTGAAGCGGACCAAGTCGGTGACCAAGCTGGAGCGGACCAAGCGCGGATCCGGCGGACTGAGGGGCTCCCGCTCGCACGAGAGTCTGCTGTCCAGTCACGCCGTCATGTCCACCATAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0261570-'10-9,'10-8,15-9=AN
Average complexity
A_C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.520 A=0.696 C2=0.583
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
FBpp0309493
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0291973, FBpp0291974, FBpp0291975, FBpp0291976, FBpp0291977, FBpp0309494, FBpp0309495, FBpp0309496
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGAAGACACTGCCTCGCATAC
R:
CTATGGTGGACATGACGGCG
Band lengths:
188-309
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)