DmeEX6023986 @ dm6
Exon Skipping
Gene
FBgn0265998 | Doa
Description
The gene Darkener of apricot is referred to in FlyBase by the symbol DmelDoa (CG42320, FBgn0265998). It is a protein_coding_gene from Dmel. It has 16 annotated transcripts and 16 polypeptides (11 unique). Gene sequence location is 3R:28888073..28922772. Its molecular function is described by: kinase activity; ATP binding; protein kinase activity; protein serine/threonine kinase activity. It is involved in the biological process described with 14 unique terms, many of which group under: multicellular organism development; visual system development; negative regulation of biological process; positive regulation of immune system process; embryo development. 88 alleles are reported. The phenotypes of these alleles manifest in: intracellular organelle; cellular anatomical entity; interommatidial bristle; sex comb; extracellular matrix. The phenotypic classes of alleles include: phenotype; increased mortality; stress response defective; increased mortality during development.
Coordinates
chr3R:28889021-28890100:+
Coord C1 exon
chr3R:28889021-28889358
Coord A exon
chr3R:28889766-28889884
Coord C2 exon
chr3R:28890005-28890100
Length
119 bp
Sequences
Splice sites
3' ss Seq
CAATGTGTGTACGTTTTCAGATG
3' ss Score
8.28
5' ss Seq
GCCGTAAGT
5' ss Score
10.11
Exon sequences
Seq C1 exon
AGTTGGCGTGCACAACACTGTCTCCCAGACGTGGTGAATAAAATACCAAGTGACGTGAATTGAAGGAAAAAAAGACGATTTTCAACGTAAACGCACACTATTTTTCGGTGTGTGTGAAAAGGCCAACAAGCGTTTTCAACAACAAGCAGAAGCCAGGATTTACAGGACAACAATTGTGGATATAGCGGCAGCAGCAGCTGCTCAAAAGGCAACAACAACGGCAGCGACAGCGACGCTTCGGCCAAGCAACAACAACAGTAGCAAAGCAAAGCCAGCGGAGCGCATAGCACAAAAATCAATTTTCGCGCTCGTGAAAAATATCAGCAGCAAATTGCAAG
Seq A exon
ATGCCCAGAACAAGGAGACTCCACCACTCAAGGGATCGCTCCTCGGCGGGCACACGAGACAAGCGCCGACGACACGATACTGCCGATCATTCGCCACCCCTAGCTGAGGCCCCATCGCC
Seq C2 exon
GCCGCGCATCACCAACACACATCACACAAGATCGGCGGCCAAGCGAAGGCGACACGAGCTCGATGCCAAGAAGGCCCAGATATCCAAGGAACCCAC
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0265998-'2-6,'2-5,5-6=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
In the CDS, with uncertain impact
No structure available
Features
Disorder rate (Iupred):
C1=NA A=1.000 C2=1.000
Domain overlap (PFAM):
C1:
NA
A:
NO
C2:
NO
Main Inclusion Isoform:
FBpp0289031
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0289020, FBpp0289023, FBpp0289026, FBpp0289027, FBpp0289028, FBpp0289030
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCCAACAAGCGTTTTCAACA
R:
CGCCGATCTTGTGTGATGTGT
Band lengths:
255-374
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)